Human CD43 is a heavily O-glycosylated and sialylated transmembrane protein that is mainly found on T cells, but not on B cells.
Isotype: Murine IgG1
Immunogen: Human KG-1 tumor cells
Specificity: Antibody DFT1 recognizes epitope A of the CD43 molecule on pMN of about 135 kd (1,3).
Functional Application: Antibody DFT1 partially induces apoptosis in hemopoetic progenitor cells and also induces homopoetic aggregation.
References:
1. W.P. Stross, et al, (1989) J Clin Pathol 42:953-961.
2. Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 1697-1713.
3. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 494-497.
