Anti-CD36 mAb blocks phagocytosis of Steptococcus/LDL mixture

Adding Low density lipoprotein to FITC labeled Group A Steptococcus increased U-937 phagocytosis rate.   This effect was blocked when cells were pre incubated with Ancell anti-CD36 mAb clone SMO.

“LDL acts as an opsonin enhancing the phagocytosis of group A Streptococcus by monocyte and whole human blood”  Lulei Zhou, Runlin Han, et al. (2016) Medical Microbiology and Immunology 205(2): 155-162. PMID: 26392394

Relevant Ancell antibodies

anti-CD36