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anti-CD74 (Invariant chain, Ii)

anti-human CD74 (Invariant chain, Ii)

Human CD74 is expressed intracellularly and on the cell surface of MHC Class II positive cells such as B cells, monocytes, macrophages, Langerhans cells and dendritic cells.  CD74 has several important functions relating to antigen presentation by MHC Class II molecules (2).

mAb name/Clone: M-B741

Isotype: Murine IgG2a

Immunogen: RPMI 1788 cell line

Specificity: Antibody M-B741 recognizes the CD74 molecule of about 33 kd (1).

Immunochemistry Applications: Flow cytometry      Immunoprecipitation      Frozen Sections

References:

1.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 568-574.

2.  P. Romagnoli & R.N. Germain, (1995) J Exp Med  182: 2027-2036.

Catalog Number:

226-020 Purified (With Antibiotics)/100ug

226-030 Biotinylated/100ug

226-040 FITC Conjugate/120 tests

226-050  R-PE Conjugate/120 tests