anti-human CD64 (Fc gamma RI)
Human CD64 is a high affinity receptor for monomeric human IgG1 and IgG3 which is expressed on macrophages, monocytes, and gamma interferon induced neutrophils. CD64 plays an
important role in clearance of immune complexes and in antibody dependent cytoxicity (3, 4, 5). mAb name/Clone: 10.1 Isotype: Murine IgG1 Immunogen:
Human rheumatoid synovial fluid cells/monocytes Specificity: Antibody 10.1 recognizes the CD64 molecule of 72 kd from gene Fc gamma RIA (1, 3). Immunochemistry Applications:
Flow cytometry Immunoprecipitation Frozen Sections Western Blot Functional Application:
Antibody 10.1 blocks binding of Fc gamma RI to immunoglobin opsonized cells (1). References: 1. G.J. Dougherty, et al, (1987) Eur J Immunol 17: 1453-1459.
2. Y. Jayaram, et al, (1989) Clin Exp Immunol 75: 414-420. 3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 874-875.
4. D.L. Durden, et al, (1995) J Immunol 154: 4039-4047. 5. L.L. Marnell, et al, (1995) J Immunol 155: 2185-2193. Catalog Number: